Centuries: 15th century - 16th century - 17th century
- 2 February - Spaniard Pedro de Mendoza founds Buenos Aires, Argentina.
- Wales is united with England by an Act of Union
- Manco II revolts from Spanish rule in Peru
- Resumption of war between Francis I of France and Emperor Charles V. Francis ceases control of Savoy and captures Turin.
- Protestantism introduced in Denmark
- Portuguese Crown divides Brazil into fifteen donatory captaincies.