A.E.S. Hudson Street was a comedy television show running on ABC from March 16, 1978 through April 20, 1978. this short-lived series followed the poorly equipped Adult Emergency Service hospital on Hudson Street, on the lower west side of Manhattan. This New York City-based show was a ratings failure, even after dumping F. Murray Abraham from the role of Dr. Tony Menzies, which he played in the pilot.

In the pilot film for this half-hour program, A.E.S. stands for Ambulance Emergency Service. The pilot aired July 21, 1977.

The series cast of characters included Dr. Tony Menzies (Gregory Sierra); Nurse Rosa Santiago (Rosana Soto); Nurse Rhonda Todd (Julienne Wells); Foshko, the ambulance driver (Susan Peretz); Stawky, Foshko's assistant (Ralph Manza); Nurse Newton (Ray Stewart); Karbow, the hospital administrator (in the pilot, Irwin C. Watson, series Stefan Gierasch); Dr. Jerry Meckler (Bill Cort); Dr. Glick, the psychiatrist (Allan Miller); Dr. Sorrentino (Jane Marla Robbins); and Dr. Friedman Bob Dishy.

Danny Arnold co-created and executive produced the series, sharing the creation credits with [Tony Sheeman]] and Chris Hayward. Roland Kibbee produced, Noam Pitlik directed, and music was by Jack Elliott and Allyn Ferguson.