ABC is an abbreviation with many meanings:
- The Roman alphabet, of which A, B, and C are the first three letters.
- The television network American Broadcasting Company.
- The radio and television network Australian Broadcasting Corporation.
- The former British television company Associated British Corporation.
- The Spanish newspaper Diario ABC S.L.
- ABC is an imperative language and programming environment developed at CWI (Amsterdam, the Netherlands). It served as inspiration for the Python programming language.
- The Atanasoff Berry Computer, completed in 1942.
- ABC ALGOL is an extension of Algol 60.
- ABC 80 was a home computer around 1980.
- ABC is a musical notation language, used specially in ASCII files because of its simplicity.
- ABC is a landmark album by The Jackson Five, including future pop star Michael Jackson.
- ABC is the name of an early 1980s new wave music band fronted by Martin Fry.
- ABC Records is a recording label.
- ABC weapons: Atomic, Biological, and Chemical warfare. This abbreviation has largely been superseded by NBC, where the "N" stands for "nuclear".
- ABC stands for Atlantic Baptist College, the former name of Atlantic Baptist University in Moncton, New Brunswick, Canada.
- The Abc Conjecture is a conjecture in number theory.
- ABC is used in cryptozoology as an acronym for alien big cat.
- ABC can stand for American-Born-Chinese
- ABC islands: Aruba, Bonaire and Curaçao.
- An alcoholic beverage commission of a U.S. state or province of Canada, which often allowed only government-run ABC stores to sell liquor
