Bob Greene (b. March 10, 1947) is an American journalist, best known as an award-winning columnist for the Chicago Tribune newspaper for 24 years. Greene attracted national attention when he was forced to resign in September, 2002, after he admitted having had sex several years earlier with a then teen-aged girl, a high school student who visited Greene for a school project and had subsequently been the subject of a Greene column.

The incident attracted considerable attention partly because Greene had made a name for himself as a crusader on behalf of abused children and as an advocate of family values, notably in his best-selling book Good Morning, Merry Sunshine: A Father's Journal of His Child's First Year.

Originally from Columbus, Ohio, Greene attended Northwestern University in Chicago and became a reporter and feature writer for the Chicago Sun-Times upon graduating in 1969; within two years he had a regular column in the paper and in late 1971 a collection of his writing was published in book form. Greene first drew significant national attention with his book, Billion Dollar Baby (1975), a diary of his experiences as a roadie for rock musician Alice Cooper. Greene's primary focus remained his newspaper column, for which he won the National Headliner's Award (an American journalism group) for best column in 1977. Shortly afterward, Greene switched to the competing Chicago Tribune. Greene also began making occasional guest appearances on local television, eventually landing a commentary slot on the ABC Television Network news program Nightline.

During the 1990s Greene spent time covering Michael Jordan of the Chicago Bulls basketball team. The two formed an unlikely friendship which Greene documented in two popular books.

Greene was extremely popular as a writer but he had his critics, largely because of his syrupy sentimentality and often heavy writing. A Chicago alternative weekly newspaper ran a column called Bob Watch: We Read Him So You Don't Have To, which made fun of his work.