The District of Sarandė (Albanian: Rrethi i Sarandės) is a district in southern Albania in the Prefecture of Vlorė at around 39.88°N, 20.00°E.

The area of the district is 730 square kilometers.

According to the 2001 census, the population of the district is 35,235. According to the census of January 1993, it was 53,700.

The centre of the district is the city of Sarandė. Other places include Konispol (at the border with Greece), Ksamil (a resort), Ēukė, Vrinė and Butrint (an archeological site).

The Greek minority has a big percentage in the district. On the coast there also live Vlachs.