Main Page | See live article | Alphabetical index Epistasis is the masking of the phenotypic effects of one gene by alleles of another at another locus. A gene is epistatic when its presence suppresses the effect of the other gene. Epistatic genes are also known as inhibiting genes due to their effects on other genes which are described as hypostatic. This article is from Wikipedia. All text is available under the terms of the GNU Free Documentation License.