Main Page | See live article | Alphabetical index The fibrinolytics are a class of pharmaceuticals that act as thrombolytics by activating plasminogen to form plasmin. Activated plasmin degrades fibrin and so breaks up thrombi. The fibrinolytics are used in thrombolytic therapy of myocardial infarct and pulmonary embolisation. The most important fibrinolytics are : streptokinase alteplase reteplase tenecteplase This article is from Wikipedia. All text is available under the terms of the GNU Free Documentation License.