Hontenisse (population: 8,014) is a former municipality in the southwestern Netherlands, in the province of Zeeland. The municipality covers an area of 115.78 km² (of which 3.53 km² water).

The former municipality of Hontenisse comprises the following towns, villages and townships: Hengstdijk, Kloosterzande, Kuitaart, Lamswaarde, Ossenisse, Terhole, Vogelwaarde, Walsoorden, which are now part of Hulst.

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