- Hyperion is a Titan from Greek mythology
- Hyperion is a natural satellite of Saturn
- Hyperion is an unfinished epic poem by John Keats
- The Hyperion Cantos is a set of four novels by Dan Simmons. Hyperion is the first novel of the set.
- Hyperion is the name of a record label specialising in classical music.
- Hyperion is a comic book superhero published by Marvel Comics, and a member of Squadron Supreme.
- HMS Hyperion (1936-1940) was a British war-ship.