The inline-six engine is also known as the straight six or slant six. Its six cylinderss are configured in a single linear bank, thus inline. The firing order and mechanical arrangement of these engines make them self balancing, which means that they are capable of running with little vibration.

Some cars/trucks known to have the I-6 engine: Jeep, AMC (Eagle, Concorde), GM (Chevrolet Trailblazer/Oldsmobile Bravada), BMW (323, M3 roadster)

Diesel I-6 engines of large displacement are used in various industrial applications due to their smooth running self balanced operation.