Jungle Fever is a 1991 film directed by Spike Lee and starring Wesley Snipes and Annabella Sciorra.

The plot centres around the inter-racial romance between a successful married black executive, Flipper Purify (played by Snipes), and an Italian-American woman, Angie Tucci (played by Sciorra), at his place of work in New York. Both of them come under intense pressure from their friends and family. A sub plot considers the problems of drug use, with Purify's brother 'Gator (played by Samuel L. Jackson) a suffering addict.

The film also featured John Turturro, Halle Berry and Ossie Davis.

The title of the film reflects the plot. The term "Jungle Fever" refers to an individual's intense sexual attraction primarily to those of another race.