- Vito Genovese (1952-1959), died naturally in prison in 1969.
- Charles Lucky Luciano (1932-1936), heart attack at Naples airport in 1962.
- Albert Anastasia (1951-1957), assassinated October 25, 1957.
- Frankie Yale, assassinated July 1, 1928.
- Joe Aiello (1928-1930), assassinated October 23, 1930.
- Philip Mangano (1931-1951), assassinated April 10, 1951.
- Vincent Mangano (1931-1951), disappeared in 1951.
- Giuseppe Profaci (Joe) (1931-1962), died of cancer June 7, 1962.
- Thomas Eboli, assassinated July 15, 1972.
- Giuseppe Masseria (Joe the Boss), assassinated April 10, 1931.
- Salvatore Maranzano, assassinated September 11, 1931.
- Gaetano Reina, assassinated February 28, 1930.
- Joseph Pinzolo (1930), assassinated September, 1930.
- Gaetano Gagliano (1930-1953), natural death in 1953.
- Thomas Lucchese (1953-1967), natural death in 1967.
- Alfred Mineo, assassinated November 5, 1930.
- Steve Ferrigno, assassinated November 5, 1930.
- Tony Lombardo, assassinated September 7, 1928
