The following is a list of notable personalities who have been addicted to heroin (or other opiates) at some point during their lives.
- Chet Baker (musician)
- William S. Burroughs (writer)
- Gia Carangi (model)
- Montgomery Clift (actor)
- Kurt Cobain (musician)
- John Coltrane (musician)
- Miles Davis (musician)
- Robert Downey Jr (actor)
- Bob Dylan (singer)
- Sigmund Freud (psychiatrist)
- Boy George (singer)
- Billie Holiday (singer)
- Dennis Hopper (actor)
- John Lennon and Yoko Ono (singers)
- Rush Limbaugh (media personality)
- Little Richard (singer)
- Courtney Love (musician)
- Bela Lugosi (actor)
- Phil Lynott (musician)
- Friedrich Nietzsche (philosopher)
- Charlie Parker (musician)
- Miguel Pinero (writer, actor)
- Edgar Allan Poe (writer)
- Keith Richards (musician)
- Santiago Rusinyol (painter)
- Axl Rose (musician)
- Winona Ryder (actress)
- Will Self (writer)
- Hubert Selby Jr (writer)
- Layne Staley (musician)
- James Taylor (musician)
- Johnny Thunders (musician)
- Aleister Crowley (occultist)