MMIX is a 64-bit RISC virtual machine. MMIX was created by Donald Knuth together with significant contributions from John Hennessy and Dick Sites. Knuth will use MMIX in further editions of his multi-volume The Art of Computer Programming to illustrate machine-level aspects of programming, especially in relation to the analysis of algorithms.

Current and earlier editions of the book use MIX, MMIX's predecessor. MMIX is a completely new design, replacing MIX in its entirety.

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