- Morpheus is a god, a member of the Greek pantheon.
- Morpheus is a file sharing computer software client operated by the company StreamCast.
- Morpheus is a fictional character in The Sandman comic book published by DC Comics. In the series, he is the king of dreams.
- Morpheus is a fictional character from the film The Matrix.
- Morpheus is a fictional character from the comic strip Little Nemo