New Jersey State Highway 163 is a state highway in New Jersey, United States. Like many state highways, this highway was created when a United States highway was rerouted; the U.S. highway in this case was United States Highway 46 and this road is still known as "Old Route 46".

NJ 163 is unsigned and runs from an intersection with US 46 in Knowlton, New Jersey to a dead end next to a still-existing railroad bridge. Before December 1, 1953, US 46 used this road to get to Portland, Pennsylvania. A bridge over the Delaware River used to exist at the dead end before it washed away in a storm.