- Orion the hunter, from Greek mythology
- Orion the constellation
- Lockheed P-3 Orion, an anti-submarine warfare aircraft
- The Orion project, a proposed nuclear pulse propulsion system
- The game, Master of Orion
- The movie company, Orion Pictures Corporation
- Orion, a commune in the Pyrénées-Atlantiques département, in France
- Orion the communications satellite
- Orion the manga by Masamune Shirow
- Orion the beer from Japan
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