Resveratrol (trans-3,5,4'-trihydroxystilbene) is a substance found in the skins of certain red grapes and the roots of Japanese Knotweed (Hu Zhang in China.) It is sold as a mass-produced nutritional supplement over-the-counter in the United States.

Resveratrol is a polyphenol which is believed to have longevity-enhancing properties. Recent experiments have demonstrated that resveratrol extends the life of a yeast. The "French Paradox" (how the French live longer while consuming a high-fat diet) has also been explained in terms of resveratrol, in that the red grape skin form makes it into red wine that is consumed in France.

Resveratrol has also been determined to increase the potentcy of some antiretroviral drugs in vitro.


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