Santiago de Cuba Province is the second most populated province in the island of cuba it has about 1.2 million people and the largest city Santiago de Cuba is the main administrative centre. largest cities:
- Santiago de Cuba; 554,000 (population)
- Palma Soriano; 125,000
- Contramaestre; 88,000
- Mayari; 80,000
- San Luis; 65,000
- Songo-la maya; 50,000