Shy-Drager syndrome (named after Dr. Milton Shy and Dr. Glenn Drager, who identified this syndrome in 1960) is a rare, progressively degenerative disease of the autonomic nervous system. Its cause is not known, and there is no cure at this time.

Symptoms of this syndrome can include: dizziness or fainting when standing up (known as postural or orthostatic hypotension); incontinence; muscular tremors; impotence; dry mouth and skin; vision problems; trouble regulating body temperature due to abnormal sweating; breathing difficulties; Parkinson-like tremors.

Most people with this syndrome are disabled within 7-8 years of the initial onset of symptoms; few live longer than 15 years afterwards.