In human anatomy, the Skene's glands (also known as the lesser vestibular or paraurethral glands) are glands located on the upper wall of the vagina, around the lower end of the urethra. They drain into the urethra and near the urethral opening. The location of the Skene's glands is also known as the Gräfenberg spot or G-spot. The Skene's glands are homologous with (that is to say, the female equivalent of) the prostate gland in males.

They are probably implicated in vaginal orgasm and in the somewhat controversial phenomenon of female ejaculation.

In 2002, Emmanuele Jannini of L'Aquila University in Italy showed that there may be an explanation both for the phenomenon and for the frequent denials of its existence. Skene's glands vary in size from one woman to another, to the point where they appear to be missing entirely in some women. If Skene's glands are the cause of female ejaculation and vaginal orgasms, this may explain the observed absence of these phenomena in many women.

The clear or milky fluid that emerges (sometimes with force) during female ejaculation has a composition similar to the fluid generated in males by the prostate gland. The liquid is frequently mixed with urine that is sometimes released during the relaxation that occurs during orgasm, and with vaginal lubricating fluid.

See also:

female sexuality, female ejaculation, vaginal orgasm, G-spot, prostate, pudendal nerve

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