The Space Quest series of 6 games describes the adventures of heroic (if clumsy and none-too-bright) janitor Roger Wilco as he campaigns through the galaxy for truth, justice and really clean floors. Initially created for Sierra by the famous Two Guys from Andromeda (who made a guest appearance in SQ3), the games were mainly a vehicle for terrible puns and really silly puzzles, as Roger fights the likes of Sludge Vohaul and the Pirates of Pestulon to save the galaxy and impress girls.
Unlike the LucasArts games, miscalculations and bad choices can lead to the unfortunate (but generally hilarious) demise of your hero - followed by the dreaded "Restore/Restart" screen. You DID save your game, didn't you?

The games