- A thresher is a device that first separates the head of a stalk of grain from the straw, and then further separates the kernel from the rest of the head.
- A thresher is a type of shark, harmless to man and easily recognizable because its tail is longer than the combined length of body and head.
- USS Thresher has been the name of two United States Navy submarines: SS-200 and SSN-593.
- Thresher music is a style of garage rock that evolved in Philadelphia, Pennsylvania