Umpqua refers to two distinct groups of Native Americans that live in south central Oregon in the United States.

Upper Umpqua

The Upper Umpqua tribe is represented as the Cow Creek Band of the Upper Umpqua. The tribe signed a treaty with the U.S. federal government on September 19, 1853. The Upper Umpqua was the first Oregon tribe to sign a federal treaty. The Cow Creek Band spoke the now-extinct Takelma language. The Cow Creek Band has a reservation near the modern-day city of Roseburg, Oregon.

Lower Umpqua

The Lower Umpqua tribe is represented in modern times as one of the three Confederated Tribes of Coos, Lower Umpqua, and Siuslaw located on the southwest Oregon Pacific coast in the United States. They spoke a language close to Siuslaw.

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