Wayne County is the name of a number of counties in the United States of America, some named for the American Revolutionary War general Anthony Wayne:
- Wayne County, Indiana
- Wayne County, Michigan (This one was not named for Anthony Wayne.)
- Wayne County, New York
- Wayne County, Utah (This one was possibly named for Anthony Wayne, but the origin of the name is uncertain.)
- Wayne County (aka Jayne County) was also the psuedonym of the singer of early New York punk rock band Wayne County and the Electric Chairs.