2C-E (2,5-dimethoxy-4-ethylphenethylamine) is a psychedelic phenethylamine first synthesized by Alexander Shulgin. It is commonly active in the 10 - 25 mg range. Shulgin classified 2C-E as a member of the "magical half-dozen." Many have reported that the effects of 2C-E are not dissimilar from those of other phenethylamines.

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