Ibogaine is a psychoactive indole alkaloid derived from the rootbark of an African plant, Tabernanthe iboga. In recent years it has been increasingly noted for its ability to treat both drug and alcohol addiction. Both scientific studies and widespread anecdotal reports appear to suggest that a single administration of ibogaine has the ability to both remove the symptoms of drug withdrawal and reduce drug-craving for a period of time after administration. In addition, the drug's psychoactive properties (in large doses it can induce a dreamlike state for a period of hours) have been widely credited with helping users understand and reverse their drug-using behavior.

Studies suggest that ibogaine has considerable potential in the treatment of addiction to heroin, cocaine, crack cocaine, methadone, and alcohol, with some suggestion that it further be useful in treating tobacco dependence. It has also been suggested that the drug may have considerable potential in the field of psychotherapy, particularly as a treatment for the effects of trauma or conditioning.

A single administration of ibogaine typically has three effects useful in the treatment of drug dependence. Firstly, it causes a massive reduction in the symptoms of drug withdrawal, allowing relatively painless detoxification. Secondly, many users report, and scientific studies confirm, a marked lowering in the desire to use drugs is experienced for a period of time after taking ibogaine, typically between one week and several months. Finally, the drug's psychoactive nature is reported to help many users understand and resolve the issues behind their addictive behavior.

Ibogaine can be easily administered, in capsule form, and has no addictive effects itself. It is essentially a "one-shot" medication and, used in a clinical setting with proper client screening procedures, the drug thus far appears to be safe to use. Whilst it is rare for an individual to stop using drugs permanently from a single dose of ibogaine, as the initial component in an overall rehabilitation program the drug would appear to offer much potential.

Although approved for clinical trials (trials on humans) for the treatment of addiction in the US in the early 1990s, problems with financial backing have so hindered the development of ibogaine that, as of mid 2001, it remains undeveloped and thus unavailable to the majority of addicts worldwide. There are however a couple of private clinics, located around the Caribbean and in Mexico, that offer ibogaine treatment at prices starting around £4,000 (about US$5500), and some lay treatment providers offer lower cost treatment, without medical facilities, in Europe. In addition, ibogaine, either in pure form or as a plant extract, has become available from some lay sources on the Internet.

Ibogaine's current legal status in the UK, and much of the rest of the world, is that of an unlicensed, experimental medication, and it is not therefore an offence to possess the drug, though to act as a distributor may be breaking the law. Ibogaine is a restricted substance (possession is illegal) in some countries, including the US, Switzerland, Sweden and Belgium.

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