The Moselle (French Moselle, German Mosel) is a river flowing through France, Luxembourg and Germany, joining the Rhine river at Koblenz. Major affluents are the Ruwer and the Saar.

The Moselle valley is famous for its beautiful scenery and the excellent wine produced there. Most notably Riesling, Sylvaner, Pinot Gris and Gewürztraminer.

The river gave its name to two French départements: Moselle and Meurthe-et-Moselle.