Pepper spray is a non-lethal chemical agent which is used in riot control and personal self-defense. The active ingredient in pepper spray is capsaicin, which is a chemical derived from cayenne, paprika, or chilies. Pepper spray is also known as OC spray (from "Oleoresin Capsicum") or OC gas. The excessive use of pepper spray has been linked to lasting injuries and fatalities. See also tear gas, chemical weapon.

The scoville rating for pepper spray can be as high as 5,300,000 for police grade and much lower for civilian grade.

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