Puy-de-Dôme is a French département, number 63, named after the Puy-de-Dôme mountain.

Along with several other départements, it was created in 1790 out of the old province of Auvergne.

Préfecture (capital): Clermont-Ferrand.

Sous-préfectures: Ambert, Issoire, Riom and Thiers.