Main Page | See live article | Alphabetical index Main Page | See live article | Alphabetical index Yeast artificial chromosome A yeast artificial chromosome (short YAC) is a biological vector used to clone large DNA fragments (up to 400 kb). It is an artificially constructed chromosome and contains the telomeric, centromeric, and replication origin sequences needed for replication in yeast cells. See also : plasmid, cosmid This article is from Wikipedia. All text is available under the terms of the GNU Free Documentation License.